By Helmut Buschmann, J?rg Holenz, Antonio Párraga, Antoni Torrens, José Miguel Vela, José Luis D?az
Antidepressants and similar psychiatric medications are an important prescribed drugs around the world, accounting for a marketplace quantity of 20 billion US$ consistent with yr. This instruction manual presents a whole and particular assessment of all presently on hand psychiatric medications, overlaying greater than 250 diverse compounds.
specific gains include:
* an important info at the chemistry, pharmacology and healing use of a given drug
* a unique format with margin notes and compound buildings taking into consideration quickly and straightforward entry to the specified information
Written by way of drug builders from the pharmaceutical undefined, novel medicinal drugs at the moment lower than improvement and new equipment of remedy are indexed part by means of facet with classical medications, permitting a right away comparability of conventional and cutting edge healing approaches.Content:
Chapter 1.1 Introductory and uncomplicated points (pages 2–50): Luz Romero, Ana Montero, Begona Fernandez and Jose M. Vela
Chapter 1.2 Clinics (pages 51–110): Rosario Perez?Egea, Victor Perez, Dolors Puigdemont and Enric Alvarez
Chapter 1.3 Pharmacology (pages 111–140): Begona Fernandez, Luz Romero and Ana Montero
Chapter 1.4 Experimental study (pages 141–172): Ana Montero, Begona Fernandez and Luz Romero
Chapter 1.5 Chemistry (pages 173–296): Jorg Holenz, Jose Luis Diaz and Helmut Buschmann
Chapter 2.1 Introductory and simple elements (pages 298–334): Francesc Artigas
Chapter 2.2 Clinics (pages 335–388): Salvador Ros and Francisco Javier Arranz
Chapter 2.3 Pharmacology (pages 389–448): Analia Bortolozzi, Llorenc Diaz?Mataix and Francesc Artigas
Chapter 2.4 Experimental examine (pages 449–489): Pau Celada, Anna Castane, Albert Adell and Francesc Artigas
Chapter 2.5 Chemistry (pages 491–616): Antonio Parraga, Jorg Holenz and Helmut Buschmann
Chapter 3.1 Introductory and uncomplicated features (pages 618–880): Francisca Lopez?Rios, Serafin Gomez?Martin and Antonio Molina?Moreno
Chapter 3.2 Clinics (pages 881–894): Blanca Gutierrez and Jorge Cervilla
Chapter 3.3 Pharmacology (pages 895–922): Jose Manuel Baeyens
Chapter 3.4 Experimental examine (pages 923–949): Enrique Portillo and Jose M. Vela
Chapter 3.5 Chemistry (pages 951–1087): Monica Garca?Loapez, Susana Yenes, Helmut Buschmann and Antoni Torrens
Chapter 4.1 Introductory and uncomplicated features (pages 1090–1103): Javier Burgueno, Rafael Franco and Francisco Ciruela
Chapter 4.2 Clinics (pages 1105–1154): Francisco Javier Arranz and Salvador Ros
Chapter 4.3 Pharmacology (pages 1155–1182): Francisco Ciruela, Rafael Franco and Javier Burgueno
Chapter 4.4 Chemistry (pages 1183–1196): Jorg Holenz, Jose Luis Diaz and Helmut Buschmann
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Extra resources for Antidepressants, Antipsychotics, Anxiolytics: From Chemistry and Pharmacology to Clinical Application
2001). , 1998). , 2004) and this may offer insights for novel therapeutic targets.
An integrative approach to depression: genetic and environmental factors (adapted from Wong and Licinio, 2001). , 1994). Allelic variations in the serotonin transporter (5-HTT) gene are of great interest in depression. A polymorphism in the 5' promoter region consisting of a short (s) and a long (l) allele with the s-allele being associated with decreased 5HT transmembrane transport and reduced transporter mRNA has been described. , 2001). , 2003). , 2002). , 2004). These individuals respond much faster to antidepressants and have a higher recurrence of depressive episodes than individuals without this mutation.
C2H4. XL Molecular modeling Molecular modeling is a technique for the investigation of molecular structures and properties using computational chemistry and graphical visualization techniques in order to provide a plausible three-dimensional representation under a given set of circumstances (IUPAC). Monoamine neurotransmitters Samal molecule neurotransmitters that contain a single amine group. Monoamines include dopamine, serotonin, noradrenaline and adrenaline, and histamine is sometimes also included in this group.
Antidepressants, Antipsychotics, Anxiolytics: From Chemistry and Pharmacology to Clinical Application by Helmut Buschmann, J?rg Holenz, Antonio Párraga, Antoni Torrens, José Miguel Vela, José Luis D?az